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- Case Report
- MR Imaging of Disseminated Tuberculosis of the Brain in a Patient with Miliary Tuberculosis : Initial Findings and Changes Six Months after Antituberculous Therapy
- Jae Ho Jang, Jae Woo Lim, Soon Lee Jung, Kyuchul Choeh, Taeil Han
- Clin Exp Pediatr. 2002;45(12):1596-1600. Published online December 15, 2002
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A 23-month-old girl visited with chronic cough and her chest radiograph showed miliary tuberculosis. There was no neurological abnormality. But CSF findings showed WBC 22/mm3(lymphocyte 20%, neutrophil 80%) and positive result of polymease chain reaction(PCR) for M. tuberculosis. MR imaging showed multiple ring enhanced nodules and ovoid nonenhancing bright signal lesion on the cerebrum, cerebellar parenchyme, and left basal ganglia.... -
- A Case of Aseptic Meningitis Following Administration of Intravenous Immunoglobulin in A Patient with Idiopathic Thrombocytopenic Purpura
- Su Jin Kim, Ji Eun Kim, Hei Won Hwang, Ji Sun Mok, Dong Seok Lee, Doo Kwun Kim, Sung Min Choi, Woo Taek Kim
- Clin Exp Pediatr. 2001;44(7):823-826. Published online July 15, 2001
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Intravenous immunoglobulin(IVIG) has been widely used to treat idiopathic thrombocytopenic purpura in childhood. Aseptic meningitis has been reported as a rare complication of IVIG therapy. This report is on an 11 year-old boy with ITP who suffered from aseptic meningitis following the administration of IVIG. He was given 1 g/kg of IVIG for 2 days, and on the fourth day... -
- Original Article
- Change of Cerebrospinal Fluid Ferritin in Children with Meningitis
- Mee Hee Youm, Eun Young Kim, Young Jong Woo, Hyun Ju Park, Chan Jong Kim
- Clin Exp Pediatr. 2000;43(8):1068-1073. Published online August 15, 2000
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Purpose : Despite the advent of new and more potent antibiotics, mortality and morbidity rates due to bacterial meningitis remain stagnant. Rapid detection of microorganism and early antibiotics treatment are the most important prognostic factors of bacterial meningitis. For early diagnosis of bacterial meningitis biochemical markers such as lactic dehydrogenase, lactic acid, C-reactive proteia have been measured in cerebrospinal fluid.... -
- The Clinical Significance of Cerebrospinal Fluid Interleukin-6 Levels in Viral Meningitis
- Eun Joo Ju, In Chul Ahn, Jae Ho Lee
- Clin Exp Pediatr. 2000;43(4):496-501. Published online April 15, 2000
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Purpose : Cytokines found at a inflammatory site may be a good indicator of clinical severity of an infectious inflammatory disease. We assayed interleukin 6(IL-6) concentrations in cerebrospinal fluid(CSF) from patients affected with viral meningitis, and verified the relationship between IL-6 and inflammatory parameters and whether IL-6 can be used as a diagnostic marker in the diagnosis of viral meningitis. Methods... -
- Diagnostic Value of Urine Latex Test In Bacterial Meningitis
- Seung Min Lee, Eun Ae Park, Seung Joo Lee
- Clin Exp Pediatr. 2000;43(1):55-59. Published online January 15, 2000
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Purpose : Bacterial meningitis in childhood carries significant mortality and morbidity, so accurate and rapid diagnosis is important. Cerebrospinal fluid(CSF) latex agglutination test has been used for rapid diagnosis of bacterial meningitis. However, urine may be the best specimen for a latex test, because bacterial antigens are concentrated in the urine. The study tried to determine the diagnostic value of urine latex test in... -
- Changes of Interleukin-10 and Granulocyte Colony-Stimulating Factor in Cerebrospinal Fluid of Children with Aseptic Meningitis
- Byeong Chan Park, Jung-Yeon Shim, Jeong Mi Lee, Jin-Young Park, Myung Ja Yoon, Hye Rim Jung, Moon Soo Park, Dong Hyeuk Keum, Dong Keug Keum
- Clin Exp Pediatr. 1999;42(12):1676-1682. Published online December 15, 1999
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Purpose : Interleukin(IL)-10 is an antiinflammatory cytokine produced by monocytes/macrophages. Granulocyte colony-stimulating factor(G-CSF) plays an important role, not only as a hemopoietic factor but also as a regulating factor for a biologic defense system by neutrophils, in the foci of infection. We studied G-CSF and IL-10 levels in the serum and cerebrospinal fluid(CSF) of patients with aseptic meningitis and investigated... -
- Clinical Study of Aseptic Meningitis from 1996 to 1998 in Chounju Presbyterian Medical Center, Korea
- Seung Woo Paik, Byoung Lae O, Sun Ja Cho, Young Taek Chang
- Clin Exp Pediatr. 1999;42(6):765-770. Published online June 15, 1999
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Purpose : There was an explosive prevalence of aseptic meningitis for three years from 1996 to 1998. In this study, we reported the time of outbreak, clinical manifestation, CSF examination of patient, and CSF virus culture. Methods : We reviewed clinical records of 794 aseptic meningitis patient who had been admitted to Chounju Presbyterian Medical Center. The total number of patients... -
- Case Report
- A Case of Mollaret Meningitis
- Sun Young Kim, Eu Jun Yang, Sang Uk Nam
- Clin Exp Pediatr. 1999;42(1):122-127. Published online January 15, 1999
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Mollaret meningitis is a recurrent aseptic meningitis with characteristic clinical features and Mollaret cells in cerebrospinal fluid. Since Mollaret first reported Mollaret meningitis in 1944, further reports had been made mainly in Europe. The syndrome consists of brief attacks of meningitis that recur at regular intervals and alternate with a symptom-free period lasting for weeks or months. The symptoms subside... -
- Original Article
- The Diagnostic Value of CSF Tumor Necrosis Factor-α for Early Diagnosis of Bacterial Meningitis
- So Young Park, Soo Ja Hwang, Eun Ae Park, Jung Wan Seo, Seung Joo Lee
- Clin Exp Pediatr. 1998;41(8):1078-1083. Published online August 15, 1998
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Purpose : During the course of bacterial meningitis, TNF-α produced by macrophages and monocytes in response to LPS and other inflammatory and immune stimulation, is now recognized as a primary mediator in the pathogenesis of infection, injury and inflammation and in the process of host defence. TNF-α was increased vascular permeability by inducing morphologic and structural changes of endothelial cells... -
- Case Report
- A Case of Chorea in the Recovery Phase of Pneumococcal Meningitis
- Eun Ah Suh, Dong Un Kim, Yoon Kyung Lee, Bung Jun Choi, Young In Kim, Ik Jun Lee
- Clin Exp Pediatr. 1998;41(5):719-723. Published online May 15, 1998
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Movement disorders(chorea, athetosis, ballism) are a rare complication that develops during the course of bacterial meningitis although associations with tuberculous meningitis are established to some extent. Movement disorders are generally believed to reflect injury to the basal ganglia, thalamus, cerebellum and cerebral cortex. Ischemic infarctions of these areas have been proposed as the cause of dyskinesias in bacterial meningitis. We... -
- Original Article
- Prognosis of Bacterial Meningitis based on Cerebrospinal Fluid Culture
- Yun Ju Lee, Won Sung Lee, Kyoung Sim Kim, Ki Bok Kim
- Clin Exp Pediatr. 1998;41(5):614-621. Published online May 15, 1998
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Purpose : The present study was undertaken to assess whether the results of cerebrospinal fluid (CSF) culture are related to prognosis. Methods : Subjected to this study were 51 cases admitted to our department who had been diagnosed as bacterial meningitis. They were divided into two groups, Group Ⅰ(20) with positive CSF culture and Group Ⅱ(31) with negative outcome, then both... -
- Clinical Studies of Aseptic Meningitis in Pusan Area in 1996
- Ji Yeon Hur, Tag Soo Kim, Woo Je Cho, Sung Won Kim
- Clin Exp Pediatr. 1998;41(1):38-46. Published online January 15, 1998
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Purpose : We report clinical features and viral studies on 153 children with aseptic meningitis in the Pusan area in 1996 and compare the results of this study with those of other reports in 1990 and 1993. Methods : One hundred fiffy-three children with aseptic meningitis who have been admitted to the Department of Pediatrics, St. Benedict Hospital between July and October 1996 were... -
- An Epidemic of Aseptic Meningitis in Summer 1996 and Global Analysis and Comparision of It with 1993
- Jung Ah Chung, Young Jun Kim, Ha Joo Choi, Woo Kap Chung
- Clin Exp Pediatr. 1997;40(8):1081-1090. Published online August 15, 1997
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Purpose : In the Summer 1996, there was an outbreak of aseptic meningitis without sequele. 116 cases who were admitted to our Department during a six month period from May to October, 1996. Therefore, we report epidemic of aseptic meningitis in 1996 and analyze and compare it with a epidemic of aseptic meningitis in 1993. Methods : We studies about clinical manefestation and laboratory finding... -
- Trend of Tuberculous Meningitis since 1970
- Jeong A Park, Chang Weon Oh, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
- Clin Exp Pediatr. 1996;39(11):1527-1537. Published online November 15, 1996
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Purpose : The incidence of tuberculous meningitis has reportedly decreased from 4.2% in 1970 to 1.8% in 1990 in Korea; however, tuberculous meningitis, which spreads hematogenously, claiming majority of mortality in childhood tuberculosis, still poses serious problems. This study was performed to evaluate the recent trend of tuberculous meningitis. Methods : We compared with three groups of tuberculous meningitis, two were our previous reports on... -
- Report of Nationwide Epidemiology of Aseptic Meningitis Outbreak in 1993 in Korea
- Sung Hee Oh, Moo-Song Lee, Jin Han Kang, Chang Hwi Kim, Chong Young Park, Young Mo Sohn, Hoan Jong Lee, Chung Sik Chun, Sang Mann Shin
- Clin Exp Pediatr. 1996;39(1):42-52. Published online January 15, 1996
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Purpose : There has been no nationwide report pertaining to the epidemiology of aseptic meningitis, although a great numer of patients have been diagnosed of the illness. Therefore, we report an explosive outbreak of aseptic meningitis occured in a nationwide scale in 1993. Methods : Aseptic meningitis epidemiology surveillence was performed retrospectively on the patients diagnosed of aseptic meinigitis from January... -
- Case Report
- A case of Neurologic Sequelae and a Case of Peripheral Gangrene of Extremities Associated with Haemophilus influenzae Type b Meningitis
- Clin Exp Pediatr. 1995;38(10):1429. Published online October 15, 1995
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Haemophilus influenzae type b(Hib) is one of the most common organisms causing bacterial meningitis in children aged between 2 months and 6 years. Since introduction of Hib vaccination, the mortality from Hib meningitis has fallen, but major neurologic sequelae, ie, mental retardation, seizure, blindness, and persistent motor deficits, are serious problems. Cerebral infarction was rarely complicated during the course of meninigitis... -
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- Original Article
- Epidemic Aseptic Meningitis in 1993 -Focused on Virus Culture-
- Ji Yeon Cho, Hyang Ju Kim, Ghee Young Jung, Jin Keun Pang, Du Bong Lee
- Clin Exp Pediatr. 1995;38(7):901-906. Published online July 15, 1995
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Purpose : Aseptic meningitis is relatively common disease caused by virus, however in most of casesthe main causes are unnoticed since virus culture and isolation is quiet difficult in our country. Authors of this thesis have conducted virus culture and isolation test to figure out cause of aseptic meningitis that was prevalent through out the country from June to July... -
- A Clinical Observation of Kawasaki Meningitis and Viral Meningitis
- Jae-Ho Hyun, Young-Hoon Kim, Ji-Whan Han, Jong-Wan Kim, Kyung-Tai Whang
- Clin Exp Pediatr. 1995;38(6):794-803. Published online June 15, 1995
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Purpose : This study was performed to investigate the clinical characteristics in Kawasaki meningitis and viral meningitis. Methods : A clinical observation and comparison were carried out on 37 patients of Kawasaki disease with meningitis(group A) and 28 patients of Kawasaki disease without meningitis (group B) who were admitted to Catholic Medical Center from July, 1991 to June, 1993 and 100... -
- Changes of Interleukin-6 Level in Serum and CSF in Aseptic Meningitis
- Moon Kyu Kim, Dong Soo Kim
- Clin Exp Pediatr. 1995;38(5):625-632. Published online May 15, 1995
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Purpose : Aseptic meningitis is an infection of CNS caused by virus and there are remarka-ble changes in endogenous cytokine level. Interleukin-6 is a pleiotropic and multi-functional cyt-okine and plays a central role in host defense mechanisms. We studied the IL--6 level in serum and CSF with the patients of aseptic meningitis and investigated the relationship of IL-6 with C... -
- The Therapeutic Effects of Dexamethasone Therapy in Neonate with Bacterial Meningitis
- Eun Gyung Lee, Kook In Park, Min Soo Park, Moon Sung Park, Ran Namgung, Chul Lee, Dong Kwan Han
- Clin Exp Pediatr. 1995;38(5):602-611. Published online May 15, 1995
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Purpose : In experimental models of meningitis and in children with meningitis, dexametha-sone has been shown to reduce meningeal inflammation and to improve the outcome of disea-se. We studied the effects of dexamethasone administration in neonates(<2 month-old) with b-acterial meningitis. Methods : We retrospectively reviewed the medical records of 30 neonates admitted to the nursery, the Yonsei University College of Medicine... -
- The Variations of CSF Glucose-To-Blood Glucose Ratio according to the Time of Blood Sampling in Asepetic Meningitis
- Dong Gui Jang, Yong Seok Choi, Mee Kyoung Lee, Chang Hee Kim, Dong Jin Lee
- Clin Exp Pediatr. 1994;37(12):1687-1692. Published online December 15, 1994
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The Measurement of CSF glucose and CSF glucose-to-blood glucose ratio is a very useful laboratory test for the differential diagnosis of meningitis. We have observed the change of blood glucose & CSF glucose-to-blood glucose ratio according to the time of blood sampling in 84 patients with aseptic meningitis who had been admitted to the department of peditrics, Dong Kang hospital... -
- Clinical and Epidemic Studies of Aseptic Meningitis
- Dong Yoon Kim, Koo Pong Jung, Heung Keun Oh, Chang Ok Soh, Jin Young Jung
- Clin Exp Pediatr. 1994;37(10):1420-1426. Published online October 15, 1994
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- Detection of Enterovirus in Patients with Aseptic Meningitis by Reverse Transcription and Polymerase Chain Reaction
- Souck Joong Yoon, Sung Jin Hong, Young Hyuk Lee, Min Hee Kim, Kyo Sun Kim, Kyu Hyun Park, Jae Myun Lee, Won Young Lee
- Clin Exp Pediatr. 1994;37(9):1226-1234. Published online September 15, 1994
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The aim of this study was to determine the applicability of reverse transcription and polymerase chain reaction(RT/PCR) for routine diagnostic use and for the detection of enteroviral mentigitis, Primers were selected in the highly conserved part of the 5'-non-coding region of the enteroviral genome. Enteroviral RNA was detected by the RT/PCR in routinely collected cerebrospinal fluids(CSF) of patients with aseptic... -
- Case Report
- A Case of Cerebral Infarction and Subdural Hemorrhage after Aseptic Meningitis
- Hyun Mi Kim, Si Whan Koh, Kyung Hwan Oh, Young Chang Kim, Sang Joo Lee
- Clin Exp Pediatr. 1994;37(5):707-711. Published online May 15, 1994
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After aseptic or septic meningitis, some neurologic complications such as convulsions, delirium, rigidity, cerebral infarctions and cerebral hemorrhage can be developed. The cerebral infarction after meningitis is caused by arterial or venous occlusions. Involvement of small perforating arteries leads to ganglionic infarcts while severe sapsm of major vessels may lead to massive infarctions in the distribution of middle and/or anterior... -
- Original Article
- Clinical Observation of Neonatal Group B β-Hemolytic Streptococcal Meningiti
- Yeon Chung Chung, Mi Won Kim, Yong Kyu Lee, Yun Jong Kang, Jung Wan Seo, Jin Keun Chang
- Clin Exp Pediatr. 1994;37(3):347-355. Published online March 15, 1994
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Neonatal meningitis caused by the Group Bβ-hemolytic streptococcus was first reported in 1958. In recent years this organism has assumed major importance in the etiology of neonatal infection. In Korea, this organism is likely to play an increasing role in neonatal infection. So this investigation was designed to report the 9 cases of Group B β-hemolytic streptococcus infected neonates admitted to... -
- Clincal Study on 12 Cases of Neonatal Group B β-Hemolytic Streptococcal Meningitis
- Won Jin Kim, Sang Woog Lee, Sang Lak Lee, Myung Sung Kim, Chin Moo Kang
- Clin Exp Pediatr. 1993;36(11):1507-1515. Published online November 15, 1993
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A clinical study was made on 12 cases of neonatal Group Bβ-hemolytic streptococcal(=GBS)meningitis, who were admitted to the department of Pediatrics, Dong-San Hospital, Keimyung University during the period of 3 years from Aug 1989 to Jul 1992. The following results were obtained 1) GBS was cultured in 12 cases(57.1%) among 21 neonatal meningitis admitted during the same period. 2) Male and female ratio... -
- Hand, Foot and Mouth Disease Associated with the Aseptic Meningitis in Seoul, 1990
- Young Ah Lee, Sei Ho Oh, Soo Jong Hong, Young Hwue Kim, Hyung Nam Moon, Chang Yee Hong
- Clin Exp Pediatr. 1993;36(6):842-849. Published online June 15, 1993
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We performed clinical and virological studies on 79 children with hand, foot and mouth disease(HFMD) who had been admitted or visited to the department of Pediatrics, Asan Medical Center from February to August, 1990. The results were as follows; 1) There were total of 79 cases with hand, foot and mouth disease during this period. The aseptic meningitis was combined in 18cases(22.8%) 2)... -
- Clinical Observation of Aseptic Meningitis Associated with Mucocutaneous Lymph Node Syndrome
- Jae Hee Han, Seon Jin Ji, Mee Kyung Namgoong, Hae Yong Lee, Jae Seung Yang, Baek Keun Lim
- Clin Exp Pediatr. 1993;36(6):805-809. Published online June 15, 1993
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Clinical observation was carried out for 147 patients with mucocutaneous lymph node syndrome(MCLS) who were admitted to the Department of Pediatrics, Wonju Cristian Hospital during the period from June, 1983 to June, 1992. A spinal tap was performed on 114 of these patients and the following results were obtained. 1) The incidence of aspetic meningitis in patients with MCLS was 52.6%.(60... -
- Aseptic Meningitis in 1991 - isolation of causative agent -
- Yoon Ah Park, Eun Young Cho, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
- Clin Exp Pediatr. 1993;36(4):506-511. Published online April 15, 1993
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To know the causative agent of asptic meningitis, we performed blood and cerebrospinal fluid study on 24 children who had been admitted to the department of Pediatrics, Asan Medical Reference Laboratory, Japan. The most of the patients were young infants, and 15 cases of them were under 3 months of age. The male to female ratio was 1:1.4. We observed the main symptoms... -
- A Clinical Study on Aseptic Meningitis Combined with Polio-Like Paralysis
- Woong Young Moon, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Chul Suh, Si Joon Yu, In Young Seong, Young Min Ahn
- Clin Exp Pediatr. 1993;36(4):485-494. Published online April 15, 1993
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We clinically reviewed four patients who were suffering from aseptic meningitis combined with polio-like paralysis and performed radiological, neurological and virological studies on them. Three patients were admitted to the department of Pediatrics. Asan Medical Center from March to August 1990, and one patient was admitted to the department of Pediatrics, Kangnam General Hospital. The results were as follows: 1) During the period... -
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Impact Factor4.2
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6.52022CiteScore92nd percentilePowered by
